For pathologies of the nervous system, complex therapy is often carried out, including the administration of antioxidants and B vitamins. These drugs include Mexidol and Kombilipen.
How to act on the body
Mexidol has a nootropic, antihypoxic, anxiolytic, stress protective, anticonvulsant, lipid-lowering effect. Combibile compensates for the deficiency of vitamins in the body.
What helps Combilipen and Mexidol
The drugs can be used simultaneously with chronic and acute disorders of cerebral circulation, cerebrostia, alcoholism (for relieving withdrawal syndrome, treating alcoholic polyneuropathy and encephalopathy).
How to apply
The solution of Mexidol is administered intravenously (streamed, drip) or intramuscularly. When performing infusions, the drug is diluted in a solution of sodium chloride 0.9%. Tablets are taken orally, three times a day, 125-250 mg. Up to 1200 mg of the drug in ampoules and up to 800 mg in tablets can be used per day.
Combilipen's injections are given intramuscularly, 2 ml per day for 5-10 days. Then they are placed less often (twice or three times a week) or they switch to pills. The latter take 1 pc. 1-3 times a day. The duration of therapy is determined by the doctor.
Where to put the injection
Kombilipen enter in / m, and Mexidol - in / m or / in.
How painful injections of Kombilipen
Injections of the drug are palpable, but not painful. The composition of Combilipen includes lidocaine, which reduces the intensity of discomfort.
Before starting therapy, you should read the special instructions listed in the instructions for use.
Pregnancy and lactation
Drugs are undesirable to use during lactation and gestation.
Medicines are not prescribed to children, since it is not known how safe such therapy is.
There are no special instructions concerning the use of drugs in old age.
Side effects of Mexidol and Combibipen
Undesirable effects listed by manufacturers: dyspeptic reactions, allergies, drowsiness, dizziness, tachycardia, confusion, arrhythmia, bradycardia, sweating, convulsions, acne, dryness in the mouth.
Contraindications to the use of Mexidol and Combibipen
The drugs are not prescribed for hypersensitivity to their components, breastfeeding, pregnancy, treatment of children.
An additional contraindication to the use of Mexidol is an acute impairment of renal or hepatic function. Kombilipen not prescribed for heart failure (acute and chronic decompensated).
Impact on driving
During therapy, side effects may develop that affect the speed of reaction and concentration of attention. People operating any means of transport should be careful.
Interaction with other drugs
Mexidol is compatible with all drugs that are used to treat somatic diseases. The drug increases the effectiveness of antidepressants, benzodiazepines, anxiolytic, anti-parkinsonian and anticonvulsant drugs. Reduces the toxic effect of ethanol.
Combibile is incompatible with ascorbic acid and heavy metal salts. Ethanol prevents the absorption of thiamine, and Levodopa reduces the effectiveness of vitamin B6. During therapy should not take multivitamin complexes with vitamins of group B.
It is necessary to take into account that thiamine is incompatible with reducing and oxidizing substances, Riboflavin, Dextrose, benzylpenicillin, Phenobarbital and sodium metabisulphite. In solutions containing sulfites, it decomposes.
Compatibility with alcohol
Drugs are prohibited to take with ethanol. Alcohol exacerbates the course of existing diseases, interferes with the normal absorption of drugs. The result is a decrease in the effectiveness of therapy.
An overdose of Mexidol is accompanied by drowsiness, and Combibipen - dizziness, tachycardia, sweating, nausea, vomiting, urticaria, itching.
If the condition is caused by oral medication, it is necessary to flush the stomach and take the sorbent. Symptomatic treatment is also recommended.
Pharmacy sales terms
Both products are prescription only.
Store the preparations in dry, dark places at temperatures up to + 25 ° C. The exception is Kombilipen ampoules (they are stored at + 2... + 8 ° C).
Mexidol retains properties for 3 years, Kombilipen - for 2 years. After this time, no medication can be used.
Mexidol analogues include drugs:
- Emoxibel and others
Analogues of Combilipen are drugs:
- Neurorubin, etc.
The cost of Mexidol is 250-1600 rubles, and Combilipen - 150-550 rubles.
Anastasia I., therapist, Moscow: “My colleagues often prescribe Mexidol for cerebral disorders. blood circulation, mild traumatic brain injury, hormonal disturbances, vascular dystonia and other pathologies. In some cases, you can additionally prick Kombilipen - group B vitamins. "
Igor, 55, Omsk: “I used drugs for coronary heart disease along with other drugs prescribed by the doctor. Earlier during the treatment, headaches appeared, but in this case they did not exist. ”
Ekaterina, 49, St. Petersburg: “I used to suffer from pancreatitis and osteochondrosis with severe pain, but they cannot be compared with what I experienced in intercostal neuralgia. Kombilipen helped to get rid of unpleasant sensations. ”