MEXIDOL AND FESAM: can I take at the same time (compatibility)

Disorders of cerebral circulation often require complex therapy. Among the drugs prescribed for such pathologies include Mexidol and Fezam.

Mexidol and Fezam are prescribed in the complex therapy of disorders of cerebral circulation
Mexidol and Fezam prescribed in the complex therapy of disorders of cerebral circulation.

How to act on the body?

Mexidol supplies tissues with oxygen, increases the body's resistance to the effects of damaging factors (shock, ischemia, hypoxia, poisoning by neuroleptics and ethanol), restores vegetative functions, helps with behavioral and cognitive violations. The drug is effective in the adhesion of platelets, atherosclerotic vascular lesions, cerebral hemodynamic disorders.

Fezam is a combined agent whose active ingredients reduce vascular resistance and improve blood flow to the brain. The drug has a nootropic, antihypoxic and vasodilating effect.

What is the difference?

The active ingredient of Mexidol is ethylmethylhydroxypyridine succinate. There are 2 dosage forms: tablets, solution for intramuscular or intravenous injection.

Fezam is a complex preparation based on cinnarizine and piracetam. Available in capsule form only.

Which is better: Mexidol or Fezam?

Answering the question which medicine is better is difficult. When choosing a drug, the diagnosis, the severity of the pathology, the individual characteristics of the organism are taken into account.

The advantage of Fezam is that he is better tolerated. Low toxicity allows using it for treating pregnant women and children over 5 years old.

To quickly improve your well-being, it is recommended to use Mexidol, which is available as a solution for intravenous and intramuscular injection.

Fezam’s low toxicity allows it to be used to treat pregnant women and children over 5 years old.
Fezam’s low toxicity makes it suitable for treating pregnant women and children over 5 years old.

Indications for use

The simultaneous use of drugs is possible, because their active substances enhance the action of each other. Drugs are prescribed for circulatory disorders in the brain, asthenia, head injuries and their consequences, neurosis-like conditions, autonomic disorders with headaches, irregular blood pressure, dizziness, drowsiness, low performance.

In which case the tool will not help?

Drugs are not used to treat conditions not listed in the instructions for use. They may also be ineffective in severe disorders and pathologies.

How to take Mexidol and Fezam together?

Drugs can be used as part of complex therapy, but between doses you need to take breaks (at least 1 hour).

Therapy should not be too long, because the simultaneous intake of drugs adversely affects the state of the internal organs (liver and kidneys).

Special instructions for the use of Mexidol and Fezam

Before you begin treatment, you need to learn specific instructions for the use of drugs.

Pregnancy and lactation

Mexidol is prohibited to use during lactation and gestation.

Fezam rarely prescribed to pregnant women, if the expected benefit to the patient exceeds the threat to the fetus. It is impossible to breastfeed during therapy, since piracetam is excreted with milk.


Fezam can be taken from 5 years.

It is not recommended to use Mexidol for the treatment of children, but some pediatricians prescribe the drug to patients over 12 years old.

Mexidol is prohibited to use during lactation and gestation.
Mexidol is prohibited to use during lactation and gestation.

Elderly age

Specific guidance on the use of funds in old age does not exist.

Side effects

During treatment with Mexidol, allergic, dyspeptic and dyspeptic reactions may occur.

Fezam's intake may be accompanied by the development of allergies, diarrhea, vomiting, nausea, abdominal pain, increased salivation, tremor. Sometimes there is an increase in sexual activity.

Side effects of the nervous system include depression, drowsiness, nervousness, hyperkinesia. In isolated cases, dizziness, headaches, problems with balance retention, ataxia, insomnia, hallucinations, anxiety, agitation were recorded.


Use of drugs is prohibited in case of intolerance to components, acute renal and hepatic insufficiency.

Fezam not used for psychomotor agitation, hemorrhagic stroke, chorea, Huntington. With caution, the drug is prescribed for Parkinson's disease, increased intracranial pressure, severe bleeding, impaired hemostasis. Keep in mind that Fezam contains lactose monohydrate.

Impact on driving

It is necessary to manage transport during treatment with caution.

Interaction with other drugs

Mexidol enhances the action of anxiolytics, benzodiazepines, antidepressants, anti-Parkinsonian and anticonvulsant drugs.

Fezam potentiates the action of antihypertensive and nootropic drugs, sometimes oral anticoagulants. Improves the tolerability of tricyclic antidepressants and antipsychotic drugs. Enhances the sedative effect of antidepressants, ethanol and drugs that inhibit the central nervous system.

Vasodilator drugs enhance the effect of Fezam.

Compatibility with alcohol

Drinking alcohol during therapy is not allowed.


Overdose occurs rarely, requires symptomatic therapy.

Pharmacy sales terms

Medicines are sold by prescription.

Storage conditions

Preparations are stored at temperatures up to + 25 ° C, in dry and dark places.

Shelf life

Use medication should be within 3 years.


Analogs of Fezam: Piracesin, NooKam, Combibitel, Omaron.

Analogs of Mexidol: Neurox, Riluzole, Emoxibel, Cerecardum, Vitagamma, Hypoxen.

Drug price

A pack of Mexidol costs 230-2050 rubles, and Fezam costs 220-250 rubles.


Anna, 50 years old, Omsk: “I put Mexidol injections during asthenia. The treatment was good, despite the existing pancreatitis. ”

Oleg, 44, Saratov: “He took medication for a traumatic brain injury. They helped recover from an accident. ”

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