Mexicor and Mexidol - medicines that reduce the sensitivity of cells to hypoxia and restore the nervous system. The effect of drugs on the body is to improve the energy metabolism that occurs with the participation of glucose and oxygen. They have medications and contraindications that need to be studied before starting treatment.
Indications for use
Antihypoxants have the same indications for use. Drugs are prescribed for such pathological conditions:
- acute or chronic slowing of cerebral circulation of any origin;
- myocardial infarction (drugs can be administered in the first hours after the onset of the attack);
- ischemic stroke;
- effects of traumatic brain injury;
- atherosclerotic lesions of cerebral vessels;
- nervous disorders, depressive states;
- withdrawal syndrome arising from chronic alcoholism (medications help get rid of signs of intoxication of the body and restore vessels affected by ethanol decomposition products);
- acute and chronic pancreatitis.
What is the difference between drugs?
The difference between drugs is in sets of additional components, pharmacokinetics and list of side effects.
Characteristics of active substances
The active substances that make up Mexidol and Mexicoor have similar characteristics. The first preparation contains emoxipin and hydroxymethyl ethyl pyridine succinate. The composition of the second medication includes ethylmethylhydroxypyridine succinate. Substances have the following properties:
- neutralize the effect of free radicals;
- slow down the course of oxidative processes;
- reduce the sensitivity of tissues to oxygen deficiency;
- accelerate the splitting of glucose, accompanied by the release of energy;
- restore blood supply to the heart muscle and brain.
The composition of Mexicoor includes pure succinic acid. Emoxipin provides the penetration of this substance into the cells. Mexidol does not contain an auxiliary component, therefore it has a less pronounced antihypoxic effect.
Which is better - Mexicor or Mexidol?
It is impossible to get an exact answer to this question. The presence of succinic acid provides a higher efficiency of Mexicoor. Both drugs have the same effect in ischemic heart disease, stroke and encephalopathy. Mexicor allows faster recovery of motor and speech functions.
Compatibility between Mexico and Mexidol
Despite the fact that the negative effects of the interaction have not been identified, the combined use of Mexidol and Mexicoor is considered inexpedient.
Dosing and Administration
Dosage depends on the type of disease and the general condition of the patient. When encephalopathy pills used mexicor. The recommended daily dose is 300-400 mg. It is divided into 3 doses. When running forms are injected. For intravenous use, 100 mg of the active ingredient per day is used, for intramuscular use, 200-300 mg. In case of acute violation of cerebral blood circulation, injections are made within 5 days, after which they switch to taking pills. Mexidol dosages will be identical.
In some cases, it is necessary to reduce the dose or refuse to use drugs.
Pregnancy and lactation
The safety of solutions and tablets for the fetus and the breastfed baby has not been confirmed. Do not use medicines during pregnancy and lactation.
Antioxidants are not prescribed to patients under 18 years of age.
Mexidol and Mexicor do not have a negative effect on the human body over 65, therefore there are no restrictions on the treatment of elderly patients.
Side effects of Mexicoor and Mexidol
Side effects of drugs are similar. They arise during long-term therapy with these agents. The most common negative consequences include the following pathological manifestations:
- nausea and vomiting;
- dry mucous membranes of the mouth;
- dizziness, headache.
Drugs have identical contraindications. Drugs can not be used in the following pathological conditions:
- hypersensitivity to the components of drugs;
- acute and chronic renal failure;
- lactase deficiency;
- liver disease (with the exception of non-alcoholic fatty degeneration, in which drugs can be administered).
Impact on driving
Drugs can cause dizziness and reduce concentration of attention, therefore during the period of treatment one should refrain from controlling complex mechanisms.
Interaction with other drugs
The drug increases the effectiveness of sedatives and psychotropic, anticonvulsant and anti-parkinsonian drugs. The use of antihypoxants in combination with nootropics helps speed recovery from ischemic brain lesions.
Compatibility with alcohol
Mexidol and Mexicor minimize the toxic effects of ethanol on the nervous system.
Prolonged administration of high doses of drugs may enhance side effects. The treatment is aimed at cleansing the body and eliminating the symptoms of overdose.
Pharmacy sales terms
Cerebral blood circulation remedies can be purchased only by prescription.
Ampoules with solutions for injection should be stored in a cool, dark place.
Medicinal products are usable for 36 months from the date of manufacture.
The following drugs have a similar effect on the human body:
The average cost of 10 ampoules of Mexidol or Mexicoor is 1,100 rubles.
Vladimir, 55, cardiologist, St. Petersburg: “Mexidol and Mexicor are often prescribed for ischemic lesions of the heart muscle. They help restore blood supply to damaged tissues and speed up the healing process. Differences between drugs is the presence of an auxiliary component that increases the bioavailability of the active substance. The Mexicor stabilizes metabolic processes faster, so it is preferred for cardiological diseases. ”
Evgenia, 70 years old, Moscow: “Mexidol took in the recovery period after a heart attack. The doctor advised to use a more modern analogue of this drug. Not much difference between the drugs is not noticed. They equally cope with pains in the heart, restore blood circulation. After completing the course of treatment, the cardiogram results improved, and the state of health returned to normal. ”