MEXIFIN AND MEXIDOL: what is better and what is the difference (differences in compositions, doctors' opinions)

Mexico and Mexidol belong to the first group of antioxidant drugs. They are used for the treatment and prevention of cardiovascular and neurological diseases. Their differences are in the composition of the active and auxiliary components. There is an erroneous assumption that these medicines are one and the same medicine, but with different names.

Mexico and Mexidol are used to treat and prevent cardiovascular and neurological diseases.
Mefidin and Mexidol are used for the treatment and prevention of cardiovascular and neurological diseases.

How to act on the body?

These drugs are characterized by a similar effect on the body, which consists in neutralizing free radicals and preventing the development of aging processes. In addition, they:

  • have a positive effect on the myocardium, increase its efficiency;
  • normalize metabolic processes;
  • reduce the likelihood of developing acute vascular disease.

These 2 drugs are prescribed with complex treatment for:

  • elimination of neurosis of various origins;
  • improve psychomotor reactions;
  • improve mental performance.

pharmachologic effect

The active substance of these drugs has the following effects:

  • increases the efficiency of membrane receptors;
  • promotes the transportation of neurotransmitters and the transmission of information through synaptic cells;
  • increases the amount of dopamine in the brain cells;
  • promotes energy synthesis in mitochondria;
  • enhances the body's resistance to damage during various pathological conditions;
  • improves blood circulation;
  • reduces the rate of formation of platelet plugs and the likelihood of hemolysis;
  • increases the effects of nitropreparatov;
  • lowers cholesterol.

After a heart attack, they improve electrical activity, contractility of the heart muscle, and also favor the regeneration of the left ventricle.

What is the difference between mexicin and mexidol?

The main differences between these drugs are that Mexidol is available in 2 and 5 ml ampoules, as well as in the form of tablets. Mexicin is produced in injection vials.

There are differences in the composition of drugs. The amount of active ingredient in a mexicin product is 50 mg per 1 ml.

Mexidol also has various combinations of the active substance in its composition:

  • tablets - 125 mg;
  • ampoules of 2 ml - 100 mg;
  • ampoules of 5 ml - 250 mg.
Because mecifin is not fully investigated, it is not prescribed for brain injuries.
Since mecifin is not fully investigated, it is not prescribed for brain injuries.

Accordingly, Mexidol is more effective than mecifin due to the possibility of selecting the required dosage.

Mexico contains only one active ingredient - ethylmethylhydroxypyridine succinate in combination with water. Mexidol contains the preservative sodium metabisulphite, which is a toxic sulfur compound. It also contains 2% preservatives by weight of the active ingredient. This can lead to allergies.

Mexidol is a more studied drug, unlike Mecifin. Due to the wide range of actions, it is often assigned to use.

What's better?

Mexidol is most often prescribed:

  • with brain injury;
  • with glaucoma;
  • with myocardial infarction;
  • in the presence of purulent processes in the peritoneum.

Since Mexico has not been fully investigated, it is not prescribed for such indications.

Mecifin is safer since there is no preservative in it that can cause an allergic reaction. But when taking Mexidol, such manifestations occur infrequently. It is suitable for the treatment of chronic pathologies, since it is available in tablets.

Mexico has a better value.

Indications for use are the same for both drugs, therefore, it is necessary to select one or another agent individually.


These drugs are similar in nature. Their simultaneous reception is not appropriate, so you need to select 1 of them. If necessary, after undergoing a course of injections, mexidol may be prescribed mexidol.

Mexidol contains the preservative sodium metabisulphite, which is a toxic sulfur compound
Mexidol contains the preservative sodium metabisulphite, which is a toxic sulfur compound.

Indications for use

Both of these drugs are indicated for use in such pathologies:

  • VSD;
  • encephalopathy;
  • neurosis;
  • cognitive disorders triggered by atherosclerotic changes;
  • circulatory disorders in the brain;
  • traumatic brain injury;
  • acute myocardial infarction;
  • withdrawal syndrome on the background of alcoholism;
  • pancreatitis;
  • intoxication with antipsychotic drugs;
  • purulent-inflammatory processes in the abdomen;
  • stress;
  • asthenic conditions, shock, etc.

How to apply mefidin and mexidol?

A single dose for injections is 1-8 ml. The doctor calculates the dosage based on the diagnosis of the patient.

The amount of daily dose should not exceed 1200 mg of active ingredient. In the first days it is necessary to administer the drug intravenously. The introduction of both jet and drop method. To reduce the risk of side effects, it is necessary to apply the infusion method. After that it is allowed to inject the drug intramuscularly.

The duration of this treatment is 2 weeks. When using Mexidol in the form of tablets, you should start the course with 1-2 tablets per day and gradually increase the dose to 6 tablets. To complete the course of treatment is necessary, gradually reducing the dose. The duration of therapy may be 2 months.

special instructions

Side effects occur in cases where the patient has an increased sensitivity to sulfites. Tablets need to drink plenty of boiled water.

Pregnancy and lactation

During pregnancy and lactation, the use of these drugs is strictly prohibited.


In childhood and adolescence, these medicines are not prescribed.

Elderly age

Elderly patients rarely prescribe these drugs, and only when absolutely necessary. It is important to adjust the dose.

With abnormal liver function

The admission of these funds in the presence of violations in the liver.

In case of impaired renal function

It is contraindicated to take these drugs for kidney failure and other diseases of this organ.

Side Effects of Mefidin and Mexidol

Adverse reactions occur when the correct dosage is not followed. These include:

  • headache;
  • nausea;
  • vomiting;
  • drowsiness;
  • dizziness;
  • impaired stool;
  • belching;
  • heartburn;
  • emotional instability;
  • systolic pressure surges;
  • lack of coordination of movements;
  • lack of appetite.

Allergies such as urticaria, itching, rashes and redness on the skin can occur.


You can not use these drugs if there are absolute contraindications to their reception. Among the limitations are the following:

  • pregnancy and lactation;
  • individual intolerance;
  • acute renal and hepatic impairment;
  • age up to 18 years.

Partial contraindications are hypersensitivity to the components of drugs and bronchial asthma.

Impact on driving

It is forbidden to drive a car and other vehicles while taking these medicines. Prolonged use of tablets affects the concentration of attention and speed of reactions, causes drowsiness.

Interaction with other drugs

Mexidol and Mexico can be combined with other drugs intended for the treatment of somatic disorders. They reduce the toxic effects on the body of ethyl alcohol. In some cases, the dose should be adjusted downward, since these drugs can increase the effects of others.

Compatibility with alcohol

Such drugs are hepatoprotectors, so they can be used during withdrawal from alcoholism. Mexidol favors the restoration of the psycho-emotional state in a patient with alcohol dependence. The tool helps to maintain proper liver function.


Symptoms of overdose include:

  • clouding of consciousness;
  • disorientation in space;
  • drowsiness;
  • auditory hallucinations;
  • fainting;
  • short-term vision loss.

When these symptoms occur, first aid should be provided - gastric lavage. It is necessary to drink several liters of low concentration potassium permanganate solution and activated carbon. If the improvement does not come, the patient should be sent to a health facility where he will be assisted.

Pharmacy sales terms

These medicines are strictly prescription.

Storage conditions

Tablets and ampoules should be stored in their original packaging in a closed box, out of the reach of children and animals. The box must be ventilated from time to time. Storage temperature - not higher than + 25 ° С.

Shelf life

Both drugs have the same shelf life - 3 years. After the expiration of this period, it is strictly prohibited to accept funds.


Analogs in tablets:

  • Hypoxen;
  • Cytoflavin.

Substitutes in the form of a solution:

  • Combilipene;
  • Trigamma.

Drug price

Cost of drugs in pharmacies:

  • Mexicin (ampoules) - from 280 rubles;
  • Mexidol - from 150 rubles.


Valentin, 46 years old, Vladivostok

Traumatic brain injury had a negative impact on health: memory deteriorated, headache attacks, and vision impaired. The doctor recommended mexicin therapy. Injections were given intravenously for 14 days. As a result, the condition improved, the vision returned to normal.

Lucia, 60 years old, Nizhnevartovsk

Memory problems and migraines began to appear. Amid severe headaches, there was a fear of light. An MRI scan showed a blood circulation disorder in the brain, after which the doctor prescribed Mexidol. I was treated for 2 weeks: I took 1 tablet 3 times a day. There was a slight drowsiness in the first days of taking the medicine, then she passed.

Evgeny, 41, Vologda

I live in the megalopolis, the rhythm of life is fast, in connection with which there is a strong nervous tension and insomnia. The doctor advised mecithin to be taken for 2 weeks and then extended the course to 1 month. The state of the nervous system has improved significantly, sleep has returned to normal, and memory has improved.

Natalya, 45, Omsk

The doctor diagnosed the IRR and prescribed mexifin. After a week of taking, I felt an improvement in my health. Its active component is retained in the body for some time, which contributes to a more rapid recovery. In addition, he was appointed to receive antihypoxants in 100 mg capsules. The result is satisfied.

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