Symptoms of increased pressure without proper treatment lead to hemorrhage and cerebral ischemia. To avoid the development of adverse effects, doctors use Dibazol and Papaverine in emergency cases.
The combined effect of drugs
The action of Dibazol is aimed at inhibiting the production of type 4 phosphodiesterase enzymes. Due to this process, AMF accumulates in smooth muscle tissues. This prevents the entry of calcium ions into the cellular structures. The drug relieves spasm of internal organs, reduces the manifestation of pain, normalizes blood pressure. Effective remedy to reduce cholesterol.
Papaverine blocks the production of phosphodiesterase, thereby reducing the smooth muscle tissue. There is an expansion of blood vessels, ducts of the digestive tract. The blood flow in the coronary vessels improves, without affecting the work of the myocardium.
Indications for use
Simultaneous use of drugs is indicated for:
- spasms of smooth muscles of internal organs;
- residual effects of polio;
- peripheral paralysis of the facial nerve.
The simultaneous use of drugs is shown in emergency cases with the development of hypertensive crisis, a sharp increase in blood pressure. They help relieve spasms of the brain and reduce intracranial hypertension.
The combination of Dibazol and Papaverine
Medicines are available in tablets and injectable solution. The use of medicines depends on the type of pathological process and the patient's condition.
If the patient has a spasm of internal organs, then it is recommended to take 2 tablets of Papaverine and Dibazol.
For diseases of the nervous system, 5 mg of Dibazol and 20 mg of Papaverine are administered once a day for 7-10 days.
How is an injection done?
For the relief of symptoms of hypertensive crisis, medications are shown in proportion of 2 ml of papaverine and 4 ml of Dibazol. If the pathology is accompanied by a strong pain syndrome, then Analgin is added to the combination.
The injection is administered intravenously. Needle length reaches 8 cm. The injection site is the gluteus maximus muscle. The position of the patient - standing or lying down. During the manipulation should monitor the level of blood pressure.
Before you give an injection, you must read the instructions for use. Non-compliance with the recommendations leads to the development of undesirable reactions.
It can not be used for a long time with arterial hypertension.
Pregnancy and lactation
Not assigned to women at the stage of carrying and breastfeeding.
Simultaneous use of Papaverine and Dibazol is forbidden to children under 12 years.
The drugs are used with caution for the treatment of elderly patients.
Side effects of Dibazol and Papaverine
In most cases, medications are well tolerated. Rarely, patients have adverse symptoms in the form of:
- nausea and vomiting;
- sudden hypotension;
- rashes on the skin;
- increased sweating.
Sometimes there is a distortion of the cardiogram.
Contraindications to the use of Dibazol and Papaverina
Medicinal products are prohibited to use when:
- low blood pressure;
- atrioventricular block;
- increased seizure activity;
- internal bleeding;
- bronchial obstruction;
- respiratory failure;
- severe liver damage;
- increased intraocular pressure;
- severe heart disease;
- acute pancreatitis.
It is not recommended to apply at an increased susceptibility to active and auxiliary substances.
Impact on driving
After the procedure for 4 hours you can not drive a car and work with complex mechanisms.
Interaction with other drugs
The simultaneous use of diuretics and antihypertensive drugs leads to increased antihypertensive action.
Compatibility with alcohol
Incompatible with alcoholic beverages.
Overdose symptoms are accompanied by increased side effects.
Pharmacy sales terms
Released by prescription.
Tablets and solution are stored at room temperature in a dark and dry place.
The drugs are valid for 5 years from the date of manufacture.
Structural analogues have not.
Dibazol costs from 22 to 65 rubles.
Papaverine will cost 44-77 rubles.
Tatiana, 36 years old, Astrakhan
The father has been suffering from hypertension for more than 3 years. Periodically we call an ambulance to make an injection with Papaverin and Dibazol. Injections help quickly. There were no side effects.
Alexey Valentinovich, 38 years old, cardiologist, Tuva
Papaverine with Dibazol is a frequently used combination for intramuscular spasms and hypertensive crisis. The positive effect comes quickly. But self-administration can lead to an overdose and deterioration of the patient.