VENTER and DE-NOL: what is better and what is the difference (difference of compositions, doctors' opinions)

In diseases of the gastrointestinal tract, many people wonder what is best to take - Venter or De-Nol, since both drugs improve the condition of the gastric mucosa. These medicines have anti-inflammatory and regenerating effects.

In diseases of the digestive tract, many people take - Venter or De-Nol
For diseases of the digestive tract, many people take - Venter or De-Nol.

Characteristic Venter

The drug is available in tablets, the active component of which is sucralfate. The drug contributes to the formation of a protective film on the surface of the ulcer or erosion, stimulating the healing process and preventing the further damaging effects of hydrochloric acid.

The drug is prescribed for ulcerative and erosive lesions of the gastrointestinal tract, gastritis and increased secretory function of the stomach. Tablets are used in the treatment of NSAIDs to eliminate the negative effects on the gastrointestinal mucosa. The drug is also effective for heartburn.

The drug can cause nausea, stool disorders and dry mouth. Less common are headaches, decreased activity and allergic reactions. In some cases, the drug provokes back pain. Do not combine the drug with antacid agents. It is important to wait at least half an hour, and only then take other medicines. If lethargy and cramps occur, therapy should be discontinued. Such symptoms indicate intoxication.

De-Nol Characteristic

The drug is available in tablets, the active component of which is bismuth tri-potassium dicitrate. The drug is effective against duodenal ulcers, as well as erosive pathologies of the stomach. The drug has a weak antimicrobial effect against Helicobacter pylori. Tablets eliminate inflammation and possess astringent properties.

The drug contributes to the formation of a thin film on the surface of the ulcer, stimulating regeneration processes and preventing further progress in pathology. The drug protects the stomach from hydrochloric acid. Tablets can be used to treat ulcers, erosions, gastritis, irritable bowel syndrome, and other similar pathologies in etiology.

The drug is effective in diseases of the stomach associated with increased secretion and the presence of the bacterium Helicobacter pylori. In the latter case, the drug is recommended to be combined with antibiotics. During therapy, stomach pains, nausea and vomiting, abnormal stools and allergies can occur.

Exceeding the dosage set by the doctor is not recommended. Otherwise, it is possible to provoke intoxication with bismuth. With pill therapy, feces may change color to dark. This is a reversible effect and does not require discontinuation of treatment.

De-Nol has a weak antimicrobial action against Helicobacter pylori
De-Nol has a weak antimicrobial action against Helicobacter pylori.

Comparison of Venter and De-Nol

Drugs are similar in effect on the stomach, but have a number of differences.


Medicines are similar in indications for use and principle of action. Both drugs stimulate the repair of damaged tissues.


What is the difference between drugs:

  • active ingredients;
  • additional properties (De-Nol also has an antibacterial effect, unlike Venter);
  • worth it.

Drugs are available in different countries. Venter is made in Slovenia, and De-Nol - in the Netherlands.

What's cheaper

Cheaper Venter. It costs about 270 rubles. The price of De-Nol starts from 320 rubles.

What's better

De-Nol is considered a more effective medicine, because, in addition to the protective and regenerating effect, it also contributes to the death of the Helicobacter pylori bacteria, further eliminating inflammation. Unlike the indicated preparation, Venter does not possess such properties. An additional benefit of De-Nol is the treatment of irritable bowel syndrome.


The drugs are not recommended for severe kidney disease and intestinal obstruction. When bleeding from the gastrointestinal tract, such drugs are contraindicated. It is not recommended to start a course of treatment with these agents during pregnancy, Alzheimer's disease and during the lactation period.

Venter stimulates the recovery of damaged tissues
Venter stimulates the recovery of damaged tissues.

Opinion of doctors and patient reviews

Svetlana, 38, gastroenterologist, Moscow

Often I prescribe De-Nol with antibacterial drugs to treat stomach ulcers. I consider the drug effective and effective, but I do not recommend using it for longer than 8 weeks in order not to provoke intoxication with bismuth. Venter in my practice I use less often, because it can provoke unpleasant side effects associated with the accumulation of aluminum in the body.

Maria, 46 years old, gastroenterologist, Pskov

Preparations are not analogs. I prescribe both drugs for ulcerative and erosive lesions of the stomach, but if pancreatitis or colitis is present, I do not recommend taking such drugs. You should also not begin treatment without prior approval of the dose with your doctor. Both drugs act directionally, their effectiveness increases in combination with Omez and other proton pump inhibitors. In most cases, it is possible to completely heal the ulcer.

Valentina, 54 years old, Yekaterinburg

Took De-Nol for erosive gastritis for a month in combination with antibiotics. The stool changed color, and abdominal pain and nausea were present. At the end of the course, the unpleasant symptoms disappeared, stomach cramps were eliminated, and overall well-being improved. Additionally, I followed a diet and completely abandoned alcohol.

Maxim, 28 years old, Vladimir

Stomach pain did not give rest. Gastritis with increased secretion has been tormenting for a long time. The doctor prescribed De-Nol in combination with Nolpaza. The drug is not cheap, but the treatment was worth it. The condition returned to normal in just a week, but nausea was present for some time. Now I feel much better, the stomach no longer bothers.

Pavel, 32 years old, Voronezh

A gastric ulcer occurred while taking NSAIDs. Abdominal pains were terrible, especially on an empty stomach. The gastroenterologist has prescribed antibiotics, De-Nol and Omez. Took medication for 2 weeks. The condition quickly improved. However, antibiotics were plagued by diarrhea, which disappeared after taking probiotics. Stomach pains disappeared, burning and heaviness after eating disappeared.

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